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ChemInform Abstract: Design and Synthesis of Novel Pyrazino[2,1-a]isoquinoline Derivatives with Potent Antifungal Activity.

โœ Scribed by Hui Tang; Can-hui Zheng; Ju Zhu; Bing-yue Fu; You-jun Zhou; Jia-guo Lv

Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
41
Category
Article
ISSN
0931-7597

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Design and Synthesis of Novel Pyrazino[2
Design and Synthesis of Novel Pyrazino[2,1-a]isoquinolin Derivatives with Potent Antifungal Activity
โœ Hui Tang; Can-hui Zheng; Ju Zhu; Bing-yue Fu; You-jun Zhou; Jia-guo Lv ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 829 KB

## Abstract A series of novel pyrazino[2,1โ€__a__]isoquinolin compounds were designed, synthesized, and their antifungal activities __in vitro__ were evaluated. The results showed that all of the title compounds exhibited antifungal activities. Most of them exhibited stronger antifungal activities t