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ChemInform Abstract: Phosphonamidate and Phosphothioate Dipeptides as Potential Inhibitors of VanX.

โœ Scribed by Ke-Wu Yang; Jeffrey J. Brandt; Lisa L. Chatwood; Michael W. Crowder


Book ID
101899407
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
31
Category
Article
ISSN
0931-7597

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New Cycloalkylpyrazoles as Potential Cyclooxygenase Inhibitors. -A series of new cycloalkylpyrazoles (VI) (15 examples) are synthesized based on the 1,3-dipolar cycloaddition reaction of nitrilimines (I) with enamine (II) in order to screen their capability to inhibit human cyclooxygenase.