Phenylamino-Pyrimidine (PAP) Derivatives
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JΓΌrg Zimmermann; Giorgio Caravatti; Helmut Mett; Thomas Meyer; Marcel MΓΌller; Ni
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Article
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1996
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John Wiley and Sons
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English
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Phenylamino-pyrimidines represent a novel class of inhibitors of the protein kinase C with a high degree of selectivity versus other serindthreonine and tyrosine kinases. Steady state kinetic analysis of N-(3-[ 1 -imidazolyl]-phenyl)-4-(3-pyridyl)-2-pyrimidinamine (3, which showed potent inhibitory