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ChemInform Abstract: Pharmacological Evaluation of a Diarylmethylene-Piperidine Derivative: A New Potent Atypical Antipsychotic?

โœ Scribed by Patrice Talaga; Alain Matagne; Henrik Klitgaard


Book ID
101911790
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Pharm
โœ Y. LIAO; P. DEBOER; E. MEIER; H. WIKSTROEM ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 1 views

Synthesis and Pharmacological Evaluation of Triflate-Substituted Analogues of Clozapine: Identification of a Novel Atypical Neuroleptic. -Evaluation of triflate derivatives of clozapine and iso-clozapine shows that compound (I) is at least three times more potent than clozapine itself, indicating t