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ChemInform Abstract: Penicillin Acylase in the Industrial Production of β-Lactam Antibiotics

✍ Scribed by A. BRUGGINK; E. C. ROOS; E. DE VROOM

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
29
Category
Article
ISSN
0931-7597

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Simple strategy of reactivation of a par
Simple strategy of reactivation of a partially inactivated penicillin g acylase biocatalyst in organic solvent and its impact on the synthesis of β-lactam antibiotics
✍ Oscar Romero; José Vergara; Roberto Fernández-Lafuente; José Manuel Guisán; Andr 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB

## Abstract Some reactions of organic synthesis require to be performed in rather aggressive media, like organic solvents, that frequently impair enzyme operational stability to a considerable extent. We have studied the option of developing a reactivation strategy to increase biocatalyst lifespan