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ChemInform Abstract: Palladium Catalyzed Synthesis of 2-Trifluoromethylquinolines Through a Domino Sonogashira—Alkyne Carbocyclization Process.

✍ Scribed by Zixian Chen; Jiangtao Zhu; Haibo Xie; Shan Li; Yongming Wu; Yuefa Gong

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
41
Category
Article
ISSN
0931-7597

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Palladium-Catalyzed Synthesis of 2-Fluor
Palladium-Catalyzed Synthesis of 2-Fluoroalkyl-3-methylene-3H-indoles Through a Domino Carbopalladation/CH Activation Process
✍ Zixian Chen; Jiangtao Zhu; Haibo Xie; Shan Li; Yongming Wu; Yuefa Gong 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB 👁 2 views

## Abstract A novel palladium‐catalyzed synthesis of substituted 3‐methylene‐3__H__‐indoles from readily accessible alkynylimines has been developed. A wide variety of 2‐fluoroalkyl‐3‐methylene‐3__H__‐indoles were synthesized in moderate to good yields through this cascade carbopalladation/CH acti