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ChemInform Abstract: Palladium-Catalyzed Hydroarylation of Propiolamides. A Regio- and Stereocontrolled Method for Preparing 3,3-Diarylacrylamides.

โœ Scribed by L. A. HAY; T. M. KOENIG; F. O. GINAH; J. D. COPP; D. MITCHELL


Publisher
John Wiley and Sons
Year
2010
Weight
39 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Regio- and Stereo
โœ L. A. HAY; D. MITCHELL ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 1 views

A Regio-and Stereocontrolled Method for Preparing 3,3-Diarylacrylamides. -The Pd-catalyzed arylation of arylpropiolamides with aryliodides provides a regio-and stereoselective synthesis of 3,3-diarylacrylamides (III). By judicious choice of (I) and (II) both the (E) and (Z)-isomers can be prepared