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ChemInform Abstract: Oxidative Reactions of Azines. Part 5. Ketodihydroxylation and Coupling of 4-(γ-Pyridyl)-1,2,5,6-tetrahydropyridines with Acetone. Molecular and Crystal Structure of 3,4-Dihydroxy-4-(γ-pyridyl)-1-ethylpiperidine-2-one.

✍ Scribed by A. T. SOLDATENKOV; I. A. BEKRO; S. A. SOLDATOVA; E. GLOVER; A. TEMESGEN; L. N. KULESHOVA; V. N. KHRUSTALEV; N. D. SERGEEVA


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Oxidative Reactions of Azines. Part 5. Ketodihydroxylation and Coupling of 4-(γ-Pyridyl)-1,2,5,6-tetrahydropyridines with Acetone. Molecular and Crystal Structure of 3,4-Dihydroxy-4-(γpyridyl)-1-ethylpiperidine-2-one. -The reaction of 4-(pyridyl-4)tetrahydropyridines (I) with acetone in the presence of permanganate affords the 2-acetylmethylenetetrahydropyridines (III) by C-C bond coupling and the 2-oxo-3,4-dihydroxypiperidines (IV) by ketodihydroxylation. Selective and effective ketodihydroxylation of tetrahydropyridines (I) is observed by use of MeCN instead of acetone. -(SOLDATENKOV, A. T.; BEKRO, I. A.;


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