ChemInform Abstract: Oxazaborolidine-Mediated Reduction of Prochiral 2-Alkylidene Cycloalkanones.
β Scribed by A. F. SIMPSON; P. SZETO; D. C. LATHBURY; T. GALLAGHER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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An Optimized in situ Procedure for the Oxazaborolidine Catalyzed Enantioselective Reduction of Prochiral Ketones. -The catalyst prepared from (S)-diphenyl prolinol is found to be the best amongst several other analogues for the reduction of alkyl aryl ketones. -(PRASAD, K. R.
Highly Enantioselective Reduction of Prochiral Ketones with N,N-Diethylaniline β’ borane (DEANB) in Oxazaborolidine-Catalyzed Reductions. -A variety of prochiral ketones (I) is enantioselectively reduced to the corresponding alcohols (II) using diethylaniline borane in the presence of a chiral oxazab
## Abstract The chiral amine synthesized from Lβvaline methyl ester and 5βchloro salicylaldehyde proves as good catalyst for the enantioselective oxazaborolidine reduction of prochiral ketones.