ChemInform Abstract: Organocatalytic Enantioselective Strecker Synthesis of α-Quaternary α-Trifluoromethyl Amino Acids.
✍ Scribed by Dieter Enders; Katharina Gottfried; Gerhard Raabe
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 56 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
Takemoto′s thiourea catalyst is successfully used for the title reaction to obtain α‐amino nitriles with up to 95% enantioselectivity.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract An efficient highly diastereoselective synthesis of quaternary α‐trifluoromethyl amino acids (III) and (V) is developed via allylation of enantiopure imines of trifluoropyruvate (I).