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ChemInform Abstract: One-Pot Tandem 1,4- and 1,2-Addition of Phosphites to α,β-Unsaturated Hydrazones.

✍ Scribed by Christian V. Stevens; Ellen Van Meenen; Kurt G. R. Masschelein; Kristof Moonen; Ann De Blieck; Jozef Drabowicz

Publisher
John Wiley and Sons
Year
2008
Weight
35 KB
Volume
39
Category
Article
ISSN
0931-7597

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One-Pot Tandem 1,4–1,2-Addition of Phosp
One-Pot Tandem 1,4–1,2-Addition of Phosphites to α,β-Unsaturated Imines for the Synthesis of Glutamic Acid Analogues
✍ Kristof Moonen; Ellen Van Meenen; Annelies Verwée; Christian V. Stevens 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB

Amino phosphonates and their corresponding amino phosphonic acids are known as amino acid mimetics and, therefore, affect the physiological activity of the cell. [1] The synthesis of 1-alkylamino phosphonates by a reaction of a dialkyl phosphite and an imine under thermal conditions had been describ