ChemInform Abstract: One-Pot Synthesis of Benzothiazolines and Naphthathiazolines via Cascade ortho-Lithiation, Cyclization and Elimination of N-Arylsulfonyl Lactams.
β Scribed by John D. Harling; Patrick G. Steel; Tom. M. Woods; Dmitry S. Yufit
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 49 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
## Abstract Lithiation of ureas (I) and (VI) followed by quenching with various electrophiles, such as aldehydes (II), ketones (IV) and alkyl halides (VII) affords the corresponding 3βsubstituted isoindolinβ1βones (III), (V), and (VIII), respectively, in good yields.