𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Oligomerization of p53 upon Cooperative DNA Binding: Towards a Structural Understanding of p53 Function

✍ Scribed by Patrick Chene; Wolfgang Jahnke


Book ID
101932682
Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
33
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The effect of mutations on peptide model
✍ Julie A. Trulson; Glenn L. Millhauser πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 162 KB πŸ‘ 3 views

The tumor suppresser protein p53 has been called the "guardian of the genome." DNA damage induces p53 to either halt the cell cycle, allowing for repair, or initiate apoptosis. P53 is mutated in over 50% of human tumors and it has been proposed that many tumorigenic mutations are deleterious to p53