The kinetics of the reactions of 2-chloro-3-nitropyridine (ortho-like) and 5-nitro ( para-like) isomer with morpholine and piperidine were studied in methanol and benzene at several amine concentrations and temperatures in the range 25 -45ยฐC. The data show that k 3-NO 2 /k 5-NO 2 ratios are less tha
ChemInform Abstract: Nucleophilic Substitutions at the Pyridine Ring. Conformational Preference of the Products and Kinetics of the Reactions of 2-Chloro-3-nitro- and 2-Chloro-5-nitropyridines with Arenethiolates.
โ Scribed by E. A. HAMED; A. A. EL-BARDAN; E. F. SAAD; G. A. GOHAR; G. M. HASSAN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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The kinetics of the reaction of 2-chloro-3-nitropyridine (ortho-like) and 2-chloro-5-nitropyridine (para-like) with a series of aryloxide ions were studied in methanol at different temperatures. Plots of DH โ versus DS โ for both reactions gave good straight lines with isokinetic temperatures of 168
The reaction rates of 2-chloro-3,5-dinitropyridine 1 with a series of arylthiolates 2a-h in methanol have been measured at 25ยฐC. The products are the corresponding 2-thioaryl-3,5-dinitropyridine 3a-h. Good Hammett correlation with value ฯช1.19 was obtained suggesting an elimination-addition mechanism