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ChemInform Abstract: Nucleic-Acid Analogues with Restricted Conformational Flexibility in the Sugar-Phosphate Backbone (“Bicyclo-DNA”). Part 6. Probing the Influence of Torsion Angle γ on DNA-Duplex Stability: Synthesis and Properties of Oligodeoxynucleotides Containing ((3′S,5′S)-2′-Deoxy- 3′,5′-ethano-β-D-ribofuranosyl)adenine and -thymine (“5′-Epi- bicyclodeoxynucleosides”).

✍ Scribed by J. C. LITTEN; C. LEUMANN

Book ID
112037479
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Nucleic-Acid Analog
ChemInform Abstract: Nucleic-Acid Analogues with Restricted Conformational Flexibility in the Sugar-Phosphate Backbone (“Bicyclo-DNA”). Part 7. Synthesis and Properties of Oligodeoxynucleotides Containing [(3′S,5′S,6′R)-6′-Amino-2′-deoxy-3′,5′-ethano-β-D-ribofuranosyl] thymine (= (6′R)-6′-Amino-bicyclo-thymidine).
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ChemInform Abstract: Nucleic-Acid Analog
ChemInform Abstract: Nucleic-Acid Analogues with Constraint Conformational Flexibility in the Sugar—Phosphate Backbone ′Tricyclo-DNA′. Part 1. Preparation of [(5′R,6′R)-2′-Deoxy-3′,5′-ethano-5′,6′-methano-β-D-ribofuranosyl] thymine and -adenine, and the Corresponding Phosphoramidites for Oligonucleotide Synthesis.
✍ R. STEFFENS; C. LEUMANN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

Nucleic-Acid Analogues with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone 'Tricyclo-DNA'. Part 1. Preparation of [(5'R,6'R)-2'-Deoxy-3',5'-ethano-5',6'-methano-β-D-ribofuranosyl] thymine and -adenine, and the Corresponding Phosphoramidites for Oligonucleotide Synthesis. -An

Nucleic Acid Analogs with Constraint Con
Nucleic Acid Analogs with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone “Tricyclo-DNA”. Part 1. Preparation of [(5′R,6′R)-2′-deoxy-3′,5′-ethano-5′,6′-methano-β-D-ribofuranosyl]thymine and -adenine, and the corresponding phosphoramidites for oligonucleotide synthesis
✍ Ralph Steffans; Christian Leumann 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 German ⚖ 1019 KB

In extension of the bicyclo-DNA nomenclature (see , Foornote 3), the name tricyclo-DNA and, correspondingly, tricyclo-deoxynucleosides was chosen to denominate this type of nucleotide and nucleoside analog. ## The numbering scheme as depicted in Fig. f for nucleosides was chosen in order to be ab