ChemInform Abstract: Novel Synthetic Methodologies. Part 207. An Efficient Synthesis of [(Tosylamino)alkyl]naphthalenols by Nucleophilic Addition of Naphthalen-2-ol with N-Tosyl Imines Using Boron Trifluoride Etherate as Catalyst.

An Efficient Synthesis of [(Tosylamino)a

An Efficient Synthesis of [(Tosylamino)alkyl]naphthalenols by Nucleophilic Addition of Naphthalen-2-ol with N-Tosyl Imines Using Boron Trifluoride Etherate as Catalyst

✍ Biswanath Das; Cheruku Ravindra Reddy; Chava Sindhu; Duddukuri Nandan Kumar; Mar 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 German ⚖ 124 KB

Tosylamino)alkyl]naphthalenols have efficiently been synthesized by nucleophilic addition of naphthalen-2-ol with N-tosyl imines (derived from both aromatic and aliphatic aldehydes) in the presence of BF 3 • OEt 2 as a catalyst at room temperature. The products are formed within 5 -9 h in high yield