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ChemInform Abstract: Novel Conformationally Restricted Tetracyclic Analogues of Δ8-Tetrahydrocannabinol.

✍ Scribed by Atmaram D. Khanolkar; Dai Lu; Pusheng Fan; Xiaoyu Tian; Alexandros Makriyannis

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Novel Conformationally Restricted Tetracyclic Analogues of ∆ 8 -Tetrahydrocannabinol.

-The novel compounds are tested for their cannabinoid receptor binding activity. It is shown that the desired activity depends on the orientation of the side chain and also on the distance to phenol ring with (IX) being the most active compound. -(KHANOLKAR, AT-

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