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ChemInform Abstract: Novel Approach for the Conversion of Natural Δ3 Cephalosporin Derivatives into Corresponding Δ2 Cephalosporin Derivatives

✍ Scribed by Korrapati V. V. Rao; Ramesh Dandala; Vijay K. Handa; Anand. G. Kamat; Inti. V. Subramanyeswara Rao; Ananta Rani; Andra Naidu


Publisher
John Wiley and Sons
Year
2008
Weight
26 KB
Volume
39
Category
Article
ISSN
0931-7597

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Abstract

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Novel approach for the conversion of nat
✍ Korrapati. V. V. Prasada Rao; Ramesh Dandala; Vija Y. K. Handa; Anand. G. Kamat; 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 211 KB 👁 1 views

## Abstract magnified image A simple one pot synthetic method for the isomerization of cephem double bond from the natural 3‐position to 2‐cephem positions is affected by silylation. Thus cephalosporin acids are treated with Ntrimethylsilylacetamide (MSA) or __N,O__‐bis(trimethylsilyl)acetamide (B