## Dedicated to Prqfessor Samuel J. Danishefsky on the occasion of' his 60th birthday Due to their effective action against drug-resistant bacterial strains, the vancomycin antibiotics"] are currently receiving unprecedented attention from chemists,['] biologists, and clinic i a n ~. [ ~] As a tar
ChemInform Abstract: New Technology for the Synthesis of Vancomycin-Type Biaryl Ring Systems.
โ Scribed by K. C. NICOLAOU; X.-J. CHU; J. M. RAMANJULU; S. NATARAJAN; S. BRAESE; F. RUEBSAM; C. N. C. BODDY
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Synthesis of the Vancomycin CDE Ring System. -The synthesis of a vancomycin CDE ring system containing monochloro substituted C and E ring moieties is proposed. The procedure involves first a coupling reaction resulting in the formation of (III) with subsequent macrocyclization to form a 1:1 mixtur
Synthesis of the Trinervitane Ring System. -The synthesis of the basic tricyclic nucleus (VI) involves Robinson anellation of the multigram scale available monoprotected dione (II) and a formation of the 11-membered ring (VI) via McMurry coupling as key steps. -(DAUBEN, W. G.; LORENZ, K.