ChemInform Abstract: Synthesis of the Trinervitane Ring System.
โ Scribed by W. G. DAUBEN; K. L. LORENZ; D. W. DEAN; G. SHAPIRO; I. FARKAS
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Synthesis of the Trinervitane Ring System. -The synthesis of the basic tricyclic nucleus (VI) involves Robinson anellation of the multigram scale available monoprotected dione (II) and a formation of the 11-membered ring (VI) via McMurry coupling as key steps. -(DAUBEN, W. G.; LORENZ, K.
๐ SIMILAR VOLUMES
Synthesis of the Vancomycin CDE Ring System. -The synthesis of a vancomycin CDE ring system containing monochloro substituted C and E ring moieties is proposed. The procedure involves first a coupling reaction resulting in the formation of (III) with subsequent macrocyclization to form a 1:1 mixtur