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ChemInform Abstract: New NO Donors with Antithrombotic and Vasodilating Activities. Part 25. Hydroxylamine Derivatives.

✍ Scribed by Klaus Rehse; Tawfig Shahrouri

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
30
Category
Article
ISSN
0931-7597

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Five 1 -0ximin0-1-nitro compounds (nitrolic acids) were prepared and tested for antithrombotic and blood pressure lowering activities. 1-Nitro-ethanone l-oxime (1, ethylnitrolic acid) 2 h after oral adminisbration to rats inhibited thrombus formation by a laser beam in msenteric arterioles of rats b