ChemInform Abstract: New Methodologies for the Preparation of Drugs and Their Metabolites: Application to 1,4-Dihydropyridines Structurally Related to Calcium Channel Modulators of the Nifedipine Type

ChemInform Abstract: Synthesis and React

ChemInform Abstract: Synthesis and Reactions of Biginelli Compounds. Part 10. Synthesis and Aromatization of Dihydropyrimidines Structurally Related to Calcium Channel Modulators of the Nifedipine-Type.

✍ J. J. VANDEN EYNDE; N. AUDIART; V. CANONNE; S. MICHEL; Y. VAN HAVERBEKE; C. O. K 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

Synthesis and Reactions of Biginelli Compounds. Part 10. Synthesis and Aromatization of Dihydropyrimidines Structurally Related to Calcium Channel Modulators of the Nifedipine-Type. -By employing the "Hideg-modification" of the Biginelli reaction a number of 1,4-dihydropyrimidines (IV) (8 examples)