ChemInform Abstract: New Approaches to the Synthesis of 2-(Trifluoromethyl)indole and 2-Amino-3-(trifluoromethyl)quinoline.
β Scribed by V. M. Muzalevskiy; A. V. Shastin; E. S. Balenkova; G. Haufe; V. G. Nenajdenko
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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Rearrangement of 2-Amino-4-(trifluoromethyl)oxazoles to Hydantoins. -5-Halogenation of the oxazoles (I) with one equivalent of bromine initially furnishes 5-bromooxazoles (II) which are further transformed into the 5-acetoxyhydantoins (IV) and (V), respectively. This rearrangement takes place as a
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