A new series of N-phosphinylureas 5b, 6a-7c was synthesized and characterized by 1 H, 13 C, 31 P NMR, IR, and elemental analysis. The three-dimensional structure of 5b has been determined by X-ray crystallography. The crystal structure revealed the existence of four independent molecules. All struct
ChemInform Abstract: N-Phosphinyl Ureas: Synthesis, Characterization, X-Ray Structure, and in vitro Evaluation of Antitumor Activity.
β Scribed by Khodayar Gholivand; Nilufar Dorosti; Fatemeh Ghaziany; Manouchehr Mirshahi; Sina Sarikhani
- Book ID
- 112044617
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 31 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent