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ChemInform Abstract: N-Alkylated 3,5-Bis(arylidene)-4-piperidones. Synthetic Approaches, X-Ray Structure and Anticancer Activity.

✍ Scribed by Michael V. Makarov; Irina L. Odinets; Konstantin A. Lyssenko; Ekaterina Yu. Rybalkina; Ilya V. Kosilkin; Mikhail Yu. Antipin; Tatiana V. Timofeeva


Publisher
John Wiley and Sons
Year
2008
Weight
19 KB
Volume
39
Category
Article
ISSN
0931-7597

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N-alkylated 3,5-bis(arylidene)-4-piperid
✍ Michael V. Makarov; Irina L. Odinets; Konstantin A. Lyssenko; Ekaterina Yu. Ryba πŸ“‚ Article πŸ“… 2008 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 417 KB πŸ‘ 1 views

## Abstract magnified image In a search for cytotoxic fluorescent materials a series of N‐alkylated and N,N‐dialkylated 3,5‐bis(arylidene)piperidones was synthesized. Alkylation of 3,5‐bis(arylidene)‐4‐piperidone afforded quaternary salts only while condensation of N‐alkyl‐4‐piperidones with subst

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In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent

ChemInform Abstract: Synthesis of 3,4-Bi
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v