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ChemInform Abstract: N-(4-Methylbenzenesulfonyl)-pyrrolidines and -piperidines by a Tandem SN2—Michael Addition Reaction.

✍ Scribed by Richard A. Bunce; Jeffrey C. Allison

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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✍ Richard A. Bunce; Sharadsrikar V. Kotturi; Christopher J. Peeples; Elizabeth M. 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 69 KB 👁 1 views

## Abstract A tandem S~N~2‐Michael addition reaction has been developed for the synthesis of __cis__‐ and __trans__‐fused nitrogen and sulfur heterocycles from the __cis__ and __trans__ isomers of ethyl (±)‐(2__E__)‐3‐[2‐(iodomethyl)cyclo‐hexyl]‐2‐propenoate. Octahydro‐1__H__‐isoindole‐1‐acetic aci