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ChemInform Abstract: 4H-1-Benzopyrans by a Tandem SN2-SNAr Reaction.

✍ Scribed by Richard A. Bunce; David Rogers; Takahiro Nago; Scott A. Bryant


Publisher
John Wiley and Sons
Year
2008
Weight
27 KB
Volume
39
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES


4H-1-Benzopyrans by a tandem SN2-SNAr re
✍ Richard A. Bunce; David Rogers; Takahiro Nago; Scott A. Bryant πŸ“‚ Article πŸ“… 2008 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 313 KB

## Abstract magnified image Treatment of 2‐fluoro‐5‐nitrobenzyl bromide with active methylene compounds in the presence of excess potassium carbonate in acetone leads to the formation of highly functionalized 4__H__‐1‐benzopyrans by a tandem S~N~2‐S~N~Ar reaction sequence. The reaction works well

1-Alkyl-2,3-dihydro-4(1H)-quinolinones b
✍ Richard A. Bunce; Takahiro Nago πŸ“‚ Article πŸ“… 2009 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 110 KB

## Abstract magnified image A tandem Michael‐S~N~Ar annulation reaction has been developed for the synthesis of 1‐alkyl‐2,3‐dihydro‐4(1__H__)‐quinolinones. Success in the reaction followed expected electronic effects for the final S~N~Ar ring closure. Treatment of doubly activated 1‐(2‐fluoro‐5‐ni