ChemInform Abstract: [n + 1] Annulation Route to Highly Substituted Cyclic Ketones with Pendant Ketone, Nitrile, and Ester Functionality.
β Scribed by Robert B. Grossman; Dhananjay S. Pendharkar; Brian O. Patrick
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Enantiomerically Pure Highly Functionalized Ξ±-Amino Ketones from the Reaction of Chiral Cyclic N-(9-Phenylfluoren-9-yl) Ξ±-Amido Esters with Organolithium Reagents. -Treatment of the cyclic Ξ±and Ξ²-amino esters (II), (V), and (VIII) with organolithium compounds is found to give the corresponding keto
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Diverse Cycloaddition Chemistry Leading to Overall Michael Addition in the Reactions of 1,1-Bis(dimethylamino)-2,2-difluoroethene with Ξ±,Ξ²-Unsaturated Aldehydes, Ketones, Esters, and Nitriles. -The freshly prepared difluoro ketene aminal (I) reacts with Ξ±,Ξ²-unsaturated aldehydes or ketones via [4 +