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ChemInform Abstract: Mononitroarenes in the Oxidative Coupling of Methyl Aryl Ketones: A New Synthesis of 1,4-Diarylbutane-1,2,4-triones.

โœ Scribed by N. V. MOSKALEV; M. I. TARTYNOVA


Book ID
112036603
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Convenient Synthe
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A Convenient Synthesis of 2-Fluoro-ฮฑ-methyl[1,1'-biphenyl]-4-acetic Acid via Rearrangement of Aryl Ketones. -For the synthesis of (ยฑ)-flurbiprofen (VIII), a potent antiinflammatory agent, 4 rearrangement methods are employed. The lead tetraacetate mediated 1,2-aryl shift of (V) is quite successful