ChemInform Abstract: Monocyclic Analogues of the μ-Opioid Agonist 3,8-Diazabicyclo(3.2.1) octanes: Synthesis, Modeling, and Activity.
✍ Scribed by D. BARLOCCO; S. VILLA; W. FRATTA; P. FADDA; D. COLOMBO; L. TOMA
- Book ID
- 112028245
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
A series of trimethyipiperazine derivatives, structurally related to the Ix-agonist 3-cinnamyl-8-propionyl-3,8-diazabicyclo[3.2.1]octane, have been synthesized and teswxl in binding studies, using 3H-DAMGO as Ix-selective ligand. Their different affinity towards Ix-opioid receptors has been interpre
Trimethylpiperazines as Monocyclic Analogues of the . mu.-Opioid Agonist 3,8-Diazabicyclo(3.2.1)octanes: Synthesis, Modeling, and Activity. -The trimethylpiperazine derivatives (IV)-(VII) are tested in binding studies for µ-opioid receptors. Their different affinity towards . mu.-opioid receptors i