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ChemInform Abstract: Modified Vilsmeier Reactions of Activated Benzofurans with Indolines: Synthesis of Benzofuran-Fused Benzocarbazoles.

โœ Scribed by David St. C. Black; Robert Rezaie


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and 5ฮฑ-Re
โœ K. ISHIBASHI; K. NAKAJIMA; Y. SUGIOKA; M. SUGIYAMA; T. HAMADA; H. HORIKOSHI; T. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 41 KB ๐Ÿ‘ 1 views

Synthesis and 5ฮฑ-Reductase Inhibitory Activities of Benzofuran Derivatives with a Carbamoyl Group. -5-Carbamoyl (VII) and 6-carbamoyl derivatives (XI) are prepared and found to show inhibitory activity of human 5ฮฑ-reductase. The key step furan ring cyclization occurs by using HCl, cf. product (V),