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ChemInform Abstract: Mitsunobu N3-Alkylation of 1,3,4-Oxadiazol-2(3H)-ones.

✍ Scribed by A. Lochead; F. Galli; S. Jegham; A. Nedelec; P. George

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199926131

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Alkylation of 1-(3,4-Disubstituted Phenyl)-2-thioxo-1,2,5,6tetrahydropyrimidin-4(3H)-ones. -Alkylation of the title compounds (I), (VI), and (IX) results in the formation of S-and N-methylated derivatives. S-methylated products (III), (VII), and (X) are always the major products. In all cases, meth