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ChemInform Abstract: Low-Cost, Fast, Convenient Peptide Synthesis with HCTU and Automated Peptide Synthesizers

✍ Scribed by Christina Hood; German Fuentes; Hirendra Patel; Karen Page; Mahendra Menakuru; Jae H. Park

Publisher
John Wiley and Sons
Year
2009
Weight
15 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Ethyl 2-Cyano-2-(hydroxyimino)acetate (Oxyma): An Efficient and Convenient Additive Used with Tetramethylfluoroformamidinium Hexafluorophosphate (TFFH) to Replace 1-Hydroxybenzotriazole (HOBt) and 1-Hydroxy-7-azabenzotriazole (HOAt) During Peptide Synthesis.
✍ Sherine N. Khattab 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 20 KB 👁 2 views

## Abstract High coupling yields and a racemization depression are observed using a combination of Oxyma and TFFH in solution‐ and solid‐phase peptide synthesis.