One-Pot Synthesis of cis-Isoquinolonic A
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Limin Wang; Jijun Liu; He Tian; Changtao Qian; Jie Sun
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Article
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2005
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John Wiley and Sons
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English
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Ytterbium(III) triflate efficiently catalyzes the one-pot reaction of homophthalic anhydride with aldehydes and amines at ambient temperature to afford the corresponding cis-isoquinolonic acid derivatives in good to excellent yields with high diastereoselectivity. This method provides a novel and mu