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ChemInform Abstract: Lewis Acid-Induced Reaction of Homophthalic Anhydride with Imines: A Convenient Synthesis of trans-Isoquinolonic Acids.

โœ Scribed by N. YU; L. BOUREL; B. DEPREZ; J.-C. GESQUIERE


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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One-Pot Synthesis of cis-Isoquinolonic A
โœ Limin Wang; Jijun Liu; He Tian; Changtao Qian; Jie Sun ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 92 KB ๐Ÿ‘ 2 views

Ytterbium(III) triflate efficiently catalyzes the one-pot reaction of homophthalic anhydride with aldehydes and amines at ambient temperature to afford the corresponding cis-isoquinolonic acid derivatives in good to excellent yields with high diastereoselectivity. This method provides a novel and mu