𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Large Scale Preparation of Protected 4-Aminomethylbenzamidine. Application to the Synthesis of the Thrombin Inhibitor, Melagatran.

✍ Scribed by C. LILA; P. GLOANEC; L. CADET; Y. HERVE; J. FOURNIER; F. LEBORGNE; T. J. VERBEUREN; G. DE NANTEUIL

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Kilogram Scale Synt
ChemInform Abstract: Kilogram Scale Synthesis of the Pyrazinone Acetic Acid Core of an Orally Efficacious Thrombin Inhibitor.
✍ Fred J. Fleitz; Terry A. Lyle; Nan Zheng; Joseph D. Armstrong III; R. P. Volante πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons βš– 36 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Large-scale production of peptides using
Large-scale production of peptides using the solid phase continuous flow method. Part 2: preparative synthesis of a 26-mer peptide thrombin inhibitor
✍ Valerio Caciagli; Franco Cardinali; Fabio Bonelli; Paolo Lombardi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 115 KB πŸ‘ 2 views

A preparative method for the preparation of large peptides is described. An advantageous theoretical weight of peptide/weight of starting resin ratio (tP w /R w ) of about 0.3 was successfully experimented. The esterification of the first amino acid was realized with a racemization of less than 1%.