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ChemInform Abstract: Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst.

✍ Scribed by Isamu Shiina; Kenya Nakata; Keisuke Ono; Masuhiro Sugimoto; Akihiro Sekiguchi


Publisher
John Wiley and Sons
Year
2010
Weight
57 KB
Volume
41
Category
Article
ISSN
0931-7597

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Kinetic Resolution of the Racemic 2-Hydr
✍ Isamu Shiina; Kenya Nakata; Keisuke Ono; Masuhiro Sugimoto; Akihiro Sekiguchi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB

## Abstract A variety of optically active 2‐hydroxyalkanoates and the corresponding 2‐acyloxyalkanoates are produced by the kinetic resolution of racemic 2‐hydroxyalkanoates by using achiral 2,2‐diarylacetic acid with hindered carboxylic anhydrides as the coupling reagents. The combined use of diph