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ChemInform Abstract: Kinetic Resolution of Racemic 1-Heteroarylalkanols by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst.

โœ Scribed by Isamu Shiina; Keisuke Ono; Kenya Nakata


Publisher
John Wiley and Sons
Year
2011
Weight
29 KB
Volume
42
Category
Article
ISSN
0931-7597

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Kinetic Resolution of the Racemic 2-Hydr
โœ Isamu Shiina; Kenya Nakata; Keisuke Ono; Masuhiro Sugimoto; Akihiro Sekiguchi ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 410 KB

## Abstract A variety of optically active 2โ€hydroxyalkanoates and the corresponding 2โ€acyloxyalkanoates are produced by the kinetic resolution of racemic 2โ€hydroxyalkanoates by using achiral 2,2โ€diarylacetic acid with hindered carboxylic anhydrides as the coupling reagents. The combined use of diph