ChemInform Abstract: Isoxazole Analogues of Curcuminoids with Highly Potent Multidrug-Resistant Antimicrobacterial Activity.
β Scribed by Chatchawan Changtam; Poonpilas Hongmanee; Apichart Suksamrarn
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
The natural curcuminoids (I), obtained from the medical plant Curcuma longa L., are structurally modified by alkylation, dealkylation, heterocyclization as well as reduction/oxidation reactions.
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## Identification of Novel Nucleotide Phosphonate Analogues with Potent anti-HCMV Activity. -In connection with another work on dioxolanes a novel series of tetrahydrofuran analogues such as (IX) and (X) are prepared. Among all compounds the derivative (IX) together with its corresponding trans-i