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ChemInform Abstract: Identification of Novel Nucleotide Phosphonate Analogues with Potent anti-HCMV Activity.

✍ Scribed by Paul Nguyen-Ba; Nathalie Turcotte; Leonard Yuen; Jean Bedard; Miguel Quimpere; Laval Chan

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Identification of Novel Nucleotide Phosphonate Analogues with

Potent anti-HCMV Activity.

-In connection with another work on dioxolanes a novel series of tetrahydrofuran analogues such as (IX) and (X) are prepared. Among all compounds the derivative (IX) together with its corresponding trans-isomer obtained from (V) are the most active substances. The structure-activity relationships are discussed. -(NGUYEN-BA, PAUL;

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