ChemInform Abstract: Iridium-Catalyzed Asymmetric Hydrogenation of Olefins Using TIQ Phosphine—Oxazoline Ligands.
✍ Scribed by Sai Kumar Chakka; Byron K. Peters; Pher G. Andersson; Glenn E. M. Maguire; Hendrik G. Kruger; Thavendran Govender
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 49 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The title reaction affords high enantiomeric excesses but also a high substrate dependence is observed.
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## Abstract Herein we describe the synthesis of a new class of chiral phosphine‐oxazolines and their application as ligands in iridium‐catalyzed hydrogenations. Mechanistic aspects of olefin hydrogenation with this class of iridium catalysts are discussed and a selectivity model to help rationalize
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