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ChemInform Abstract: Inhibitors of the Kynurenine Pathway

✍ Scribed by Trevor W. Stone


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
31
Category
Article
ISSN
0931-7597

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Induction of the kynurenine pathway by n
✍ Maria Holtze; LinnΓ©a Asp; Lilly Schwieler; GΓΆran Engberg; HΓ₯kan Karlsson πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 180 KB πŸ‘ 1 views

## Abstract Glutamatergic NMDA (__N__‐methyl D‐aspartate) receptors play a critical role in brain development and neurotransmission. Kynurenic acid, an end product of tryptophan degradation along the kynurenine pathway, is an endogenous NMDA receptor antagonist. In the present study, the effects of