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ChemInform Abstract: Indium-Mediated Coupling of Aldehydes with Allyl Bromides in Aqueous Media. The Issue of Regio- and Diastereoselectivity.

โœ Scribed by M. B. ISAAC; T.-H. CHAN


Book ID
112029497
Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
27
Category
Article
ISSN
0931-7597

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Indium-mediated allylation of carbonyl c
โœ Teck-Peng Loh; Zheng Yin; Hong-Yan Song; Kee-Leng Tan ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 315 KB

Anomalous syn-diastereoselectivity of indium-mediated coupling of aldehydes with bromides Z-3b and E-3b is reported. The reaction afforded high syn selectivity regardless of the allylic bromide geometry. Preliminary studies on the enantioselective indium-mediated allylation were attempted and found