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ChemInform Abstract: In vivo Cardiotonic Activity of Pyridylmethylene-2-indolinones.

✍ Scribed by A. ANDREANI; A. LOCATELLI; R. MORIGI; A. LEONI; R. BOSSA; M. CHIERICOZZI; I. GALATULAS


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


In vivo Cardiotonic Activity of Pyridylmethylene-2-indolinones.

-5-Chloro-3-pyridylmethylene-2-indolinone (III) is synthesized and subjected to an in vivo cardiotonic assay along with some previously described analogues. Structure-activity relationships are discussed. -(ANDREANI, A.;


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Synthesis and Structure-Activity Relationships of 3-Hydrazono-1H-2-indolinones with Antituberculosis Activity. -Reaction of 3-thiosemicarbazonoindolinones (I) with 2-bromoacetophenones (II) provides 3-thiazolinylidenehydrazones (III) or isothiosemicarbazones (IV) in good yield. These new hydrazonoi