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ChemInform Abstract: Improved Synthesis of Valsartan (IV) via Nucleophilic Aromatic Substitution on Aryloxazoline (II).

โœ Scribed by Samir Ghosh; A. Sanjeev Kumar; R. Soundararajan; G. N. Mehta


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
41
Category
Article
ISSN
0931-7597

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Synthesis of 1-Oxacephams via Improved Cyclization of N-Substituted-4-formyloxyazetidin-2-ones. -A simple and efficient procedure for the synthesis of the 1-oxacepham skeleton from N-substituted-4-formyloxyazetidin-2-ones, readily prepared from 4-vinyloxyazetidin-2-one, is developed based on a stud