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ChemInform Abstract: How Stable Are Epoxides? A Novel Synthesis of Epothilone B.

✍ Scribed by Harry J. Martin; Martina Drescher; Johann Mulzer

Publisher: John Wiley and Sons
Year: 2010
Weight: 32 KB
Volume: 31
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200017233

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## Synthesis of Epothilones: Stereoselective Routes to Epothilone B. -In continuation of studies concerning the total synthesis of epothilones, efficient routes to epothilone B (I) using a macro-lactonization and a metathesis approach are detailed.