ChemInform Abstract: Highly Selective Ylide-Initiated Michael Addition/Cyclization Reaction for Synthesis of Cyclohexadiene Epoxide and Vinylcyclopropane Derivatives.

✍ Scribed by Ben-Hu Zhu; Rui Zhou; Jun-Cheng Zheng; Xian-Ming Deng; Xiu-Li Sun; Qi Shen; Yong Tang

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 51 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201038103

✦ Synopsis

Abstract

Treatment of α,β‐unsaturated ketones with the sulfonium salt (I) and the weak base Cs~2~CO~3~ results in efficient and stereoselective formation of cyclohexadiene epoxides like (III).