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ChemInform Abstract: Highly Regioselective and Diastereoselective Directed Hydroformylation of Allylic Ethers: A New Approach to Propionate Aldol Synthesis.

โœ Scribed by Isaac J. Krauss; Charles C.-Y. Wang; James L. Leighton


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Highly Diastereosel
โœ Varinder K. Aggarwal; Juliet K. Barrell; Julia M. Worrall; Rikki Alexander ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 36 KB

In the presence of H 2 O 2 /NaOH or tBu-O-OH the acetals (III), except (IIIc), undergo highly diastereoselective oxidation to the oxiranes (IV). The latter are versatile intermediates for the preparation of a variety of ฮฑ-heterosubstituted carbonyl compounds like ฮฑ-amino amides. -(AG-