ChemInform Abstract: Highly Diastereoselective Synthesis of 1-Pyrrolines via SnCl4-Promoted [3 + 2] Cycloaddition Between Activated Donor—Acceptor Cyclopropanes and Nitriles.

✍ Scribed by Gopal Sathishkannan; Kannupal Srinivasan

• Publisher: John Wiley and Sons
• Year: 2012
• Weight: 41 KB
• Volume: 43
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201213129

✦ Synopsis

Highly Diastereoselective Synthesis of 1-Pyrrolines via SnCl 4 -Promoted [3 + 2] Cycloaddition Between Activated Donor-Acceptor Cyclopropanes and Nitriles.

-The products are isolated as single cis diastereomers. Using standard imine chemistry, the preparation of useful derivatives such as (VI) is possible. -