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ChemInform Abstract: High-Affinity Nucleic Acid Recognition Using ′LNA′ (Locked Nucleic Acid, β-D-ribo Configured LNA), ′xylo-LNA′ (β-D-xylo Configured LNA) or ′α-L-LNA′ (α-L-ribo Configured LNA).

✍ Scribed by Vivek K. Rajwanshi; Anders E. Haakansson; Ravindra Kumar; Jesper Wengel

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

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Alpha-LNA is presented as a stereoisomer of LNA (locked nucleic acid) with alpha-D-configuration. Three different approaches towards the thymine alpha-LNA monomer as well as the 5-methylcytosine alpha-LNA monomer are presented. Different alpha-LNA sequences have been synthesised and their hybridisat