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ChemInform Abstract: Heterocycles Through Domino Reactions with Trimethyl Aconitate, a Versatile Synthetic Building Block.

✍ Scribed by Daniel Witthaut; Roland Froehlich; Hans J. Schaefer

Publisher: John Wiley and Sons
Year: 2010
Weight: 34 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200214115

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✦ Synopsis

Abstract

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Heterocycles through Domino Reactions with Trimethyl Aconitate, a Versatile Synthetic Building Block

✍ Daniel Witthaut; Roland Fröhlich; Hans J. Schäfer 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 78 KB

The multitalented synthetic reagent trimethyl aconitate (1) is a renewable raw material with a high density of functional groups that up to now has only been scarcely used as a C building block. Domino reactions with 1 consisting of imine additions and intramolecular acylations provide simple access